The bold plan to end malaria with a gene drive
How genetically engineered mosquitoes might defeat a disease that kills millions of children.
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The invention of the CRISPR gene editing tool has injected new life into a line of research called gene drive. Gene drives use selfish genetic elements to spread a modification through a wild population.
Researchers have proposed using gene drives against agricultural pests and invasive species, but the most urgent application is against vector-borne diseases like malaria, which kills hundreds of thousands of people every year, mostly in sub-Saharan Africa.
We talked to the scientists working on this revolutionary approach to disease eradication to find out how it works and how long it might take to deploy a technology like a gene drive against malaria.
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@Vox
February 26, 2026 at 8:25 pm
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– joss
@DanteGabriel-lx9bq
February 26, 2026 at 8:25 pm
There's a reason why we left the jungle and embraced society. We should use our ingenuity to make our lives better!
@rustle2
February 26, 2026 at 8:25 pm
Once it's tested on mozzies then it will be introduced by WH0 mrna vaccine mandates into selected human populations? Just a thought.
@vastcapital
February 26, 2026 at 8:25 pm
It's not right to say it's a disease affecting people in Africa. How about it's a disease that is prevalent in the tropics?
@A_E4556
February 26, 2026 at 8:25 pm
We have no right to wipe out an entire species just for doing what's in their nature to survive. We have a right to defend ourselves from mosquitoes, not seek out to destroy them.
@treesarewood-basedhe6657
February 26, 2026 at 8:25 pm
is this the Steven universe soundtrack?
@Oli_Olberius
February 26, 2026 at 8:25 pm
2023 and malaria is back in the United States. Good job.. NOT!
@namman6190
February 26, 2026 at 8:25 pm
Resistant to Malaria Parasite is good but Extinction of Mosquitoes ….That is An ethical Grey Area
Save Human Children Great But Extinction of The Mosquito Species …uh …..
@namman6190
February 26, 2026 at 8:25 pm
Now Frogs will have less Food to Eat
@TheOnlyZiTRO
February 26, 2026 at 8:25 pm
OK THIS WAS 4 YEARS AGO! WHY DO WE STILL FIGHT THIS?!
@nickc3657
February 26, 2026 at 8:25 pm
Are there many Africans opposed to these efforts on “nature” grounds? Or is it just rich westerners who don’t have anything to actually lose?
@shubhangbahadur7112
February 26, 2026 at 8:25 pm
It’s so fascinating how much the human race is achieving so so rapidly. ❤
@sqawb2728
February 26, 2026 at 8:25 pm
Where Nobel prize 💀
@RHabib548
February 26, 2026 at 8:25 pm
Awesome video
@cheddarcheese089
February 26, 2026 at 8:25 pm
Time for an update to this video.
@Dr.Glynis-Melodeon
February 26, 2026 at 8:25 pm
Excellent video.
@adnanmohammad9785
February 26, 2026 at 8:25 pm
It's all fun and games until they use this to control human population xD
@sinekonata
February 26, 2026 at 8:25 pm
Vox : See? We, your benevolent rulers, can provide solutions for your problems through the science we control. You still need us.
The rest of the world : No thank you, we're already working on how to rid ourselves of you parasites. That's the solution to all our problems. And stop calling us dictatorships thank you.
@shadowguy1112
February 26, 2026 at 8:25 pm
bio class c:
@angelitabecerra
February 26, 2026 at 8:25 pm
I'm all for getting rid of Malaria so long as we don't tank the mosquito population in the process. Mosquitoes are the basis of several food chains. We cannot afford to collapse the food web in those regions either.
I like the idea of making them unable to carry the parasite that in turn carries Malaria vs destroying the mosquito population.
@MrVip3r
February 26, 2026 at 8:25 pm
Ah yes malaria the most annoying Disease in far cry 2
@MrCharlesdick
February 26, 2026 at 8:25 pm
you seem to be confusing CRISPR with Cre-Lox.
@plowedsnow3889
February 26, 2026 at 8:25 pm
Would have been nice to have in Far Cry 2
@Retroglamamour
February 26, 2026 at 8:25 pm
Have they done phase II and III testing on the mosquito gene drives yet? 😅 Because I have a list of other species they should use gene drives on.
@DGill48
February 26, 2026 at 8:25 pm
Theodore Roosevelt: "In any moment of decision, the best thing you can do is theright thing. The next best thing is the wrong thing, and the worst thing you can do is nothing"
@curtisowen3233
February 26, 2026 at 8:25 pm
Compared to the damage already being done with insecticides we shouldn't wait a moment longer.
@liopleurodon155
February 26, 2026 at 8:25 pm
As a biologist, I can't understand the overly positive reactions. This is very destructive technology. The only thing I can compare this to is the invention of the nuclear bomb. Similar population-wide destructive force. Letting a low-trophic population collapse will send shockwaves up the food chain.
@danielcreatd872
February 26, 2026 at 8:25 pm
I wouldn't like this technology to be used. It's probably safe but even the small risk isn't worth it. You can never be too safe.
@Djwhiskers
February 26, 2026 at 8:25 pm
This is quite sus
@zm1786
February 26, 2026 at 8:25 pm
If only we could do this with humans… oh wait
@milehigh2625
February 26, 2026 at 8:25 pm
Sounds familiar with the Covid Vaccine, with the Vaccine certain humans can not have baby's
@milanfilipovic3648
February 26, 2026 at 8:25 pm
Found this video after learning about the Oxitec experiment in the Florida Keys. Really interesting!
@earlaweese
February 26, 2026 at 8:25 pm
Please make mosquitos extinct!!!
@mykingdomforahorse9256
February 26, 2026 at 8:25 pm
So man keeps messing with the delicate balance of nature created by God… thinking he can improve God's inventions, and perfect structure??? So far all it does is enslave mankind.
@Bxu021
February 26, 2026 at 8:25 pm
Instead of making the females infertile, why not just give the females a gene that kills malaria?
@walzingdewormed3425
February 26, 2026 at 8:25 pm
When the horror-show guy at 08:45 calls nature a "horror-show" , you know how wrong things are…
@badkaladoo8637
February 26, 2026 at 8:25 pm
Oh, the stupidity of frail humans. Laughable 🤣🤣🤣
@SEOTRENDING
February 26, 2026 at 8:25 pm
Why even god allow this bill gates live in this world?
@jackhillman8803
February 26, 2026 at 8:25 pm
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@fiverZ
February 26, 2026 at 8:25 pm
Modifying DNA is just a conspiracy theory guys.
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