True Facts: The Self-Sacrificing Amoeba

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Backbay Lounge Kevin MacLeod (incompetech.com)
Thank you to:
The family of Dr John Bonner, Princeton University
https://www.princeton.edu/news/2019/02/15/microbiologist-john-bonner-leading-expert-cellular-slime-molds-dies-98
Dr Jitka Cejkova, University of Chemistry and Technology Prague
https://droplets.vscht.cz/people/cejkova
Dr Thomas Gregor, Princeton University
https://phy.princeton.edu/people/thomas-gregor
Dr Kathie Hodge, Cornell University
https://cals.cornell.edu/kathie-therese-hodge
Dr Bernard Jenni, Mabritec
https://www.youtube.com/c/bernardjenni
Dr Edvin Johannesen, Natural History Museum Oslo
https://www.nhm.uio.no/
https://www.facebook.com/groups/SlimeMold
Kent Loeffler, Cornell University
http://www.plantpath.cornell.edu/plant_pathology/scene3b9f.html
Alberto Melappioni
https://www.youtube.com/c/AlbertoMelappioni
Dr Fred Spiegel, University of Arkansas
https://www.researchgate.net/profile/Frederick-Spiegel
Cornell Center for Fungal Biology
http://ccfb.cornell.edu/
Education Development Center
https://www.edc.org/
TGLab, Princeton University
https://tglab.princeton.edu/
UMass Amherst Libraries
Citations:
Bianchi, E., Doe, B., Goulding, D. et al. Juno is the egg Izumo receptor and is essential for mammalian fertilization. Nature 508, 483–487 (2014). https://doi.org/10.1038/nature13203
Bloomfield G, Paschke P, Okamoto M, Stevens TJ, Urushihara H. Triparental inheritance in Dictyostelium. Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):2187-2192. doi: 10.1073/pnas.1814425116. Epub 2019 Jan 22. Erratum in: Proc Natl Acad Sci U S A. 2019 Feb 25;: PMID: 30670662; PMCID: PMC6369745.
Bonner, J.. (2008). The social amoebae: The biology of cellular slime molds. The Social Amoebae: The Biology of Cellular Slime Molds.
Dormann D, Weijer CJ. Imaging of cell migration. EMBO J. 2006 Aug 9;25(15):3480-93. doi: 10.1038/sj.emboj.7601227. PMID: 16900100; PMCID: PMC1538568.
Kurato Mohri, Ryodai Tanaka, Seido Nagano, Live cell imaging of cell movement and transdifferentiation during regeneration of an amputated multicellular body of the social amoeba Dictyostelium discoideum, Developmental Biology, Volume 457, Issue 1, 2020, Pages 140-149, ISSN 0012-1606, https://doi.org/10.1016/j.ydbio.2019.09.014.
Kuwana S, Senoo H, Sawai S, Fukuzawa M. A novel, lineage-primed prestalk cell subtype involved in the morphogenesis of D. discoideum. Dev Biol. 2016 Aug 15;416(2):286-99. doi: 10.1016/j.ydbio.2016.06.032. Epub 2016 Jun 29. PMID: 27373689.
Mori M, Yao T, Mishina T, Endoh H, Tanaka M, Yonezawa N, Shimamoto Y, Yonemura S, Yamagata K, Kitajima TS, Ikawa M. RanGTP and the actin cytoskeleton keep paternal and maternal chromosomes apart during fertilization. J Cell Biol. 2021 Oct 4;220(10):e202012001. doi: 10.1083/jcb.202012001. Epub 2021 Aug 23. PMID: 34424312; PMCID: PMC8404465.
Orvieto, Raoul & Shimon, Chen & Rienstein, Shlomit & Jonish-Grossman, Anat & Shani, Hagit & Aizer, Adva. (2020). Do human embryos have the ability of self- correction?. Reproductive Biology and Endocrinology. 18. 10.1186/s12958-020-00650-8.
Prabhakara, K.H., Gholami, A., Zykov, V.S., & Bodenschatz, E. (2017). Effects of developmental variability on the dynamics and self-organization of cell populations. New Journal of Physics, 19.
Smith TS, Pineda JM, Donaghy AC, Damer CK. Copine A plays a role in the differentiation of stalk cells and the initiation of culmination in Dictyostelium development. BMC Dev Biol. 2010 Jun 2;10:59. doi: 10.1186/1471-213X-10-59. PMID: 20525180; PMCID: PMC2890595.
Raper, Kenneth B., and Dorothy I. Fennell. “Stalk Formation in Dictyostelium.” Bulletin of the Torrey Botanical Club 79, no. 1 (1952): 25–51. https://doi.org/10.2307/2482103.
Uchikawa T, Yamamoto A, Inouye K. Origin and function of the stalk-cell vacuole in Dictyostelium. Dev Biol. 2011 Apr 1;352(1):48-57. doi: 10.1016/j.ydbio.2011.01.014. Epub 2011 Jan 21. PMID: 21256841.
@zefrank
February 4, 2025 at 4:36 am
Go to https://brilliant.org/zefrank/ to learn!
First 200 people get 20% off the annual Premium subscription.
@lieu7enan755
February 4, 2025 at 4:36 am
i love my macrophages
@b00nz0r
February 4, 2025 at 4:36 am
Ameba unlocked humanity? 😂
@AsmodeusMictian
February 4, 2025 at 4:36 am
Jerry must be one of the most interesting human beings on the planet, given the questions and comments he comes up with!
Thanks for another awesome video! =)
@jennamiller8648
February 4, 2025 at 4:36 am
So witty! So enjoyable 😉
@securi-t
February 4, 2025 at 4:36 am
"Goodge" is my new favorite word.
@techwizardjr585
February 4, 2025 at 4:36 am
Don’t trees essentiallu
@isaiahjones6901
February 4, 2025 at 4:36 am
" Runaway dog peni" "tube like snot condom"
Too much 😅😅
@stephenlucas8862
February 4, 2025 at 4:36 am
2:25 almost doesnt look real, its so amazing looking! crazy that happens hah
@nhdcrap09
February 4, 2025 at 4:36 am
You smarty little chicken nipple 🤣
@JimmyMatis-h9y
February 4, 2025 at 4:36 am
9:02 😂 sacrificing themselves for themselves
Sounds a bit like Yahweh (sacrificing himself to himself).
@kathleensullivan4547
February 4, 2025 at 4:36 am
God spoke life and just look at it!!
@bradeyyates6280
February 4, 2025 at 4:36 am
HAHA Gary!!
@paraglidingprospector
February 4, 2025 at 4:36 am
I once spotted a bunch of those stalk cells in my backyard and always wondered what they were. Thx for answering the unanswered questions.
@lumotroph
February 4, 2025 at 4:36 am
This isn’t Disco Elysium
@mqntys6725
February 4, 2025 at 4:36 am
2:50 momjeans mentioned🗣🗣🗣🗣🗣🗣🗣
@gregorysagegreene
February 4, 2025 at 4:36 am
Single cells preempting multicellular modalities. 🤔
@DemstarAus
February 4, 2025 at 4:36 am
Shoon I too sall eat a sitload of food and divide into two versions of myshelf.
@darthembers
February 4, 2025 at 4:36 am
During any cell splitting, the parent cell gives 'birth' to daughter cells. Should've been a female name, not Richard 😢
@patrailriders6284
February 4, 2025 at 4:36 am
Hilariously awesome. A book called Lifetide by Lyall Watson brought me here.
@evelynwildman1290
February 4, 2025 at 4:36 am
“And it sort of pinches itself off like a loaf”😂😂😂 I freaking adore poop humor!
@LightBlueVans
February 4, 2025 at 4:36 am
“then it does some normal shit … just kidding” that killed me
@alldayagain
February 4, 2025 at 4:36 am
You gotta think; this is probably how multi-cell organisms started 😅
@black-snow
February 4, 2025 at 4:36 am
What the actual fuck?
@yilomina2047
February 4, 2025 at 4:36 am
Amazing as always
@e.mjohnson9675
February 4, 2025 at 4:36 am
Now what are the odds of that??
@SoirEkim
February 4, 2025 at 4:36 am
Is “Jerry” based on the “Jerry” from “Rick & Morty”?
@Redfernroses
February 4, 2025 at 4:36 am
GOOGE
@Damenwave
February 4, 2025 at 4:36 am
I read it as Disco Elysium when scrolling through the feed
@irenesteele9011
February 4, 2025 at 4:36 am
Oh my God Dickies giving you the bird
@irenesteele9011
February 4, 2025 at 4:36 am
That reminds me why I'm so afraid of ball pits
@irenesteele9011
February 4, 2025 at 4:36 am
Don't want to smell you later Richard
@irenesteele9011
February 4, 2025 at 4:36 am
Hi dicky
@irishrover4658
February 4, 2025 at 4:36 am
Excellent as usual!!
@BigBass-xf5yi
February 4, 2025 at 4:36 am
I couldn’t begin to imagine the work and research that goes into a video like this. Bravo Mr Frank.👍🏻
@PetroicaRodinogaster264
February 4, 2025 at 4:36 am
Just think…to an Amoeba, your body is its Universe!.
But seriously, when you see the organisation, synchronisation and structural changes that a single cell organism can and does go through over relatively short spans of time, it is very obvious we evolved and this god created us bunk is just the ramblings of mad men!
@bari2883
February 4, 2025 at 4:36 am
Who discovers these pulses and names the chemical released sick as amp? 😂
@Catlady77777
February 4, 2025 at 4:36 am
It's way complicated!
@misscyanic2484
February 4, 2025 at 4:36 am
These are just so cool!
@akeem2983
February 4, 2025 at 4:36 am
Slime molds seem like sort of outsiders that are trying to reinvent some of the stuff that multi-cellular things usually do. And do it so well – long time ago people just assumed that they're some another weird kind of fungi
@jeffgoode9865
February 4, 2025 at 4:36 am
This was…not what I expected from amoebi.