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Your Brain On Ayahuasca: The Hallucinogenic Drug

AsapSCIENCE | December 26, 2025



How does the popular new drug Ayahuasca affect your brain?
Your Brain on MDMA: https://youtu.be/jEAr7ThsYew
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References / Further Reading:
[1] http://www.bbc.com/news/magazine-27203322
[2] http://www.ncbi.nlm.nih.gov/pubmed/26976063
[3] http://smo.sagepub.com/content/1/2050312113508389.full
[4] http://www.nytimes.com/2014/06/15/fashion/ayahuasca-a-strong-cup-of-tea.html?_r=0
[5] http://www.ncbi.nlm.nih.gov/pubmed/25693169
[6] http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462016000100065
[7] http://www.ncbi.nlm.nih.gov/pubmed/25806551
[8] http://journal.frontiersin.org/article/10.3389/fphar.2016.00035/full
[9] http://www.ncbi.nlm.nih.gov/pubmed/8731519

Written by AsapSCIENCE

Comments

This post currently has 47 comments.

  1. @CLB.40cal

    December 26, 2025 at 2:55 am

    Seems awesome despite the fact that if you don’t cook it right you can literally die and if you take even the slightest amount to much, you’re getting sent to confront your demons and the inner mechanisms of the universe.

  2. Anonymous

    December 26, 2025 at 2:55 am

    Cool! Only the part where you said . People can’t decide if “it’s safe”.
    Indigenous people have been drinking ayahuasca for over 10.000 years.
    We don’t have the technology to fully understand this medicine, because we are not that smart yet, but they were.
    How amongst thousands and thousands of plants in the Amazon did they know how to pick this specific 2, and make them a certain way to create ayahuasca? This is technology. Not from computer, but from nature .

    For instance, we DO know alcohol and cigarettes are bad for you. Proven. And yet, it’s legal. People do it “socially”.

    Also, regarding death in ayahuasca, that has always been something from misuse , people not following protocol, etc.
    Don’t blame the medicine.
    It’s the same thing to say, oh the building was at fault because the person decided to jump off of its window.

    Time to shift the focus..

  3. @yup171y11

    December 26, 2025 at 2:55 am

    please don't call It a drug. That comes with a lot of negative connotations and it will repel some people who might have received a lot of benefit from this. It does ayahuasca a tremendous disservice to group it with drugs – Coke, heroin, GHB, etc. 

    Ayahuasca is medicine. It heals trauma, connects you to god, improves your relationships, helps you to make better decisions, Is not addictive at all and has zero come down (it has an afterglow). this is not a drug.

  4. @prueblackmore5538

    December 26, 2025 at 2:55 am

    It is clear from your description that you have never taken the journey. It is like no other and have experienced most for a variety of reasons and to journey outside of stasis into an expanded state of awareness. The work has been underground around the world for decades now and you are playing catch up however neuroscience is adding to the picture biologically.

  5. @muirick9924

    December 26, 2025 at 2:55 am

    READ kjv Revelation 1:14-15 in the bible. 👉Christ is described to have white wool hair & dark skin (thats what Christ YASHAYA really looks like) also 🖐🏿Daniel 10:5 & 6 .💠 Eyes like lamps of Fire 🔥 red. Like wine?
    👉💠 his arms & feet like a color of polished BRASS .
    & it does matter if the✡️ ppl (roman)) catholics converts gonna lie on Christ the 1st begotten on the father.
    ●bc what they show in Christianity is not what the bible says.
    ● & everybody knows what this 😈✡️ pentagram is ,.. star of Molock. Look up it. & their idolaters too. With all their idols. That has Nothing to do with the bible. Read Jeremiah 10.
    & read Deuteronomy 28-68 real Israelites were on slave ships to America.
    & in Revelation 2:9 Christ exposes the FAKE j3ws J3W–ISH✡️ppl. Aka ~{Romans}~ catholics & they believe in telmud & read the Kabbalah too. Those books are😈✡️. U can convert into a physical bloodline. There is no spiritual Israelites.
    (do your research) ✡️are esau, edomites 👉👈👈👉👉

  6. @muirick9924

    December 26, 2025 at 2:55 am

    ●Only Truth is the bible *Not religions & btw Christianity dosent = mean the bible & christ bc Christianity/ roman catholics✡️ literally dosent follow the bible. *(read the bible & then u will know, Christianity ✡️ &✝️ dosent follow the bible at all. Its all Babylonian.
    read revelation 1:14-15 btw & Deuteronomy 28-68.
    The bible says Christ is dark skinned with white wool hair btw. & isreal Gods chosen ppl in the bible is the people on slave ships to America in Deuteronomy 28-68.
    💠 ALL RELIGIONS & HOLIDAYS💠 ARE pagun aka Satanic✡️ & their Origin is from Babylon. Tower of Babyl with Nimrod, Sieramasis, & satan👈👉👉👈👈

  7. @muirick9924

    December 26, 2025 at 2:55 am

    Its satanic ✡️ & u start dealing with fallen angels & demons. (U will get possessed) Its witchcraft. The 1st drug was the tree of good & evil planted by satan✡️ in the garden.

  8. @muirick9924

    December 26, 2025 at 2:55 am

    Its satanic ✡️ & u start dealing with fallen angels & demons. (U will get possessed) Its witchcraft. The 1st drug was the tree of good & evil planted by satan✡️ in the garden.

  9. @ExtremePacifist

    December 26, 2025 at 2:55 am

    Opens doors to the spirit world where demons access our world and interact in our lives, not wise to open those doors and allow those spirits to have access to our minds, bodies, and surroundings. Only a true and personal relationship with Christ Jesus who sends His Holy Spirit to each individual who calls on the name of Jesus, can anyone be protected from these fallen angels and demonic spirits. Praise Jesus. Thank You Jesus. Maranatha Jesus. 🙏🏼✌🏽☝️🌅✝️🙏🏼

  10. @LilCaseyCupcake

    December 26, 2025 at 2:55 am

    There’s little mention here of the INCREDIBLE healing powers of this medicine. It helped me find peace with my experiences of childhood abuse, neglect, and lifetime of sexual predators, and an abusive relationship. In fact, I found beauty in all of it and in me. Now I have everything I need now to live a happy and beautiful life.

    This should not be for recreation. It’s hard hard work and if the vomiting scares you away, then you haven’t quite reached enough pain in your life to be ready for this plant.

  11. @info-ayawakening

    December 26, 2025 at 2:55 am

    After delving into the profound effects of Ayahuasca, my curiosity led me to seek a deeper understanding of the science behind this ancient brew. Dr. Gabor Maté's explorations into Ayahuasca's therapeutic potential for addiction treatment were particularly enlightening. His discoveries validated my personal experiences and urged me to delve deeper into the rabbit hole of Ayahuasca research. At Ayawakening, we focus on the scientific principles underpinning Ayahuasca's effects, ensuring a balanced blend of tradition and science in our approach.

    The science of Ayahuasca is a cornerstone for those keen on exploring this plant medicine responsibly. It's fascinating how Ayahuasca has shown promise in treating addiction, depression, and anxiety, alongside enhancing mindfulness and creativity both in the short and long term. Remarkably, in vitro studies revealed that Ayahuasca stimulates neurogenesis and augments brain plasticity during the afterglow, a phase lasting approximately 10 to 14 days post-intake​.

    Delving deeper, the pharmacology of Ayahuasca unveils a complex concoction involving the Banisteriopsis caapi vine and leaves from the Psychotria viridis plant. The vine harbors monoamine oxidase inhibitors (MAOIs) crucial for activating the psychedelic properties of N-N-dimethyltryptamine (DMT) found in the leaves. Yet, these MAOIs are more than mere activators; they possess psychoactive properties of their own, adding a layer of complexity to Ayahuasca's effects. DMT, a key component of Ayahuasca, significantly impacts neural plasticity, facilitating the brain's ability to form new neural connections. This property of DMT, alongside its potential to alleviate mood and anxiety disorders, underscores the profound healing capacity of Ayahuasca​​.

    Ayahuasca's transformative potential extends beyond merely transient experiences. It unveils a path of self-discovery and healing, rooted in both mystical tradition and scientific validation. The elucidation of Ayahuasca's neurogenic properties, its impact on mental health, and the unfolding of its complex pharmacological profile provide a rich tapestry of understanding that enhances the experience manifold.

    In founding Ayawakening, the aspiration was to bridge the ancient wisdom encapsulated in Ayahuasca with the scientific rigour of today, facilitating a deeper understanding and safer exploration of this sacred medicine. We strive to shed light on the profound science of Ayahuasca, fostering a community of enlightened and responsible explorers. Our journey is not just about personal or collective healing; it's about delving into the unknown with a spirit of inquiry and reverence.

  12. @MarkRoland-ou3qh

    December 26, 2025 at 2:55 am

    Macro vs Micro had success in doing a few Macro first . Allowing the mushrooms to blast you into self awareness , showing you the shadows and trauma that have been hiding under the rug . Micro dosing has helped me stay on the pulse of my shadow work , helping me remember my best self

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